Temozolomide (NSC 362856), DNA Alkylator
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Descrição
Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects. - Mechanism of Action & Protocol.
PDF) Phase I study of temozolomide in paediatric patients with advanced cancer
Selleck Chemical LLC Temozolomide 25mg 85622-93-1 CCRG81045, NSC 362856,TMZ
Temozolomide Cas# 85622-93-1 - GlpBio
Efficient delivery of Temozolomide using ultrasmall large-pore silica nanoparticles for glioblastoma - ScienceDirect
In search of effective therapies to overcome resistance to Temozolomide in brain tumours
Biomedicines, Free Full-Text
Biomedicines, Free Full-Text
Frontiers An overview of glioblastoma multiforme and temozolomide resistance: can LC-MS-based proteomics reveal the fundamental mechanism of temozolomide resistance?
Role of Temozolomide in the Treatment of Cancers Involving the Central Nervous System
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